Search results for "Asthma and Lower Airway Disease"

Early-life weight gain, prematurity, and asthma development.

2014

Early childhood asthma is a clinical syndrome, the development and clinical manifestations of which result from a complex interplay among airway anatomy, physiology, and inflammation. Although multiple phenotypes of early childhood wheezing and asthma have been described, the mechanisms that promote and differentiate these phenotypes remain poorly understood. Over the past decade, substantial understanding has emerged as to the early-life factors that influence childhood asthma development. One area of great interest has been the relationships between patterns of fetal and infant growth, subsequent wheezing, and asthma. Although several studies strongly suggest that intrauterine growth patt…